what medications does flaxseed interfere with

2016 Jun;67(4):461-9. 2005-2023 Healthline Media a Red Ventures Company. NSAIDs: NSAIDs are a term used for non-steroidal anti-inflammatory drugs such as ibuprofen; which when taken with HRT can decrease its ability to protect your heart. Is Flaxseed Good for Thyroid? Let's Find Out Savas BB, Alparslan GB, Korkmaz C. Effect of flaxseed poultice compress application on pain and hand functions of patients with hand osteoarthritis. Dietary fiber and breast cancer. Flaxseed - More Interactions. Flax seed and Aspirin drug interactions - eHealthMe All rights reserved. View abstract. View abstract. Flaxseed is packed with beneficial nutrients, omega-3 fatty acids, and fiber. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Advertising and sponsorship opportunities. Chan School of Public Health. View abstract. View abstract. Summary: Drug interactions are reported among people who take Flaxseed and Anastrozole. Ghaseminasab-Parizi M, Nazarinia MA, Akhlaghi M. The effect of flaxseed with or without anti-inflammatory diet in patients with rheumatoid arthritis, a randomized controlled trial. These are considered to help with lowering your cholesterol as well as lowering your chances of developing cardiovascular disease, diabetes, and even some cancers. Avoid using flax together with other herbal/health supplements that can lower blood sugar, such as alpha-lipoic acid, chromium, devil's claw, fenugreek, garlic, guar gum, horse chestnut, Panax ginseng, psyllium, Siberian ginseng, and others. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Flaxseed oil as a dietary supplement is not regulated by the U.S. Food and Drug Administration. Plasma insulin-like growth factor I levels in rats are reduced by dietary supplementation of flaxseed or its lignan secoisolariciresinol diglycoside. 2013 May;33(5):367-75. Int J Vitam Nutr Res. View abstract. Cat owners know that their furry little friends need the best nutrition to stay healthy and active. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Flaxseed might make these estrogen-containing drugs less effective. It also helps boost the immune system to protect against health problems. It is also used for many other conditions, but there is no good. Flaxseed can be added to hot cereal, muffins, pancakes, salads, salad dressings, yeast breads and more. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition. View abstract. . Morshedzadeh N, Shahrokh S, Aghdaei HA, et al. View abstract. Kilkkinen A, Stumpf K, Pietinen P, et al. J Nutr. View abstract. Flax may also be used for purposes not listed in this product guide. View abstract. 2016 Jun;35(3):615-25. Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer. 3 Are there some individuals who should not take black seed oil? According to Dr. Jaiswal, some of the common prescription and over-the-counter medications that interact with levothyroxine are: Antibiotics: ciprofloxacin, rifampin Seizure medications: phenytoin, fosphenytoin, and carbamazepine Antidepressants: amitriptyline, fluoxetine Am J Clin Nutr 2001;73:1094-100. 2019;29:41-48. Eur.J Clin.Nutr. Flaxseed for Constipation: How to Use Plus Other Home Remedies - Healthline Int J Food Sci Nutr. Raspberries - joint pain. What Are the Benefits of Flaxseed Oil Pills? How fast does psyllium work? You may also want to be careful combining flaxseed oil and warfarin, which is a blood-thinning medication that prevents the formation of blood clots. View abstract. 016 Sep 1;21:70. These types of drugs, herbs and supplements reduce blood clotting. Even though it's just a food, flaxseed oil may not mix well with certain health conditions or medications. Br J Nutr 1993;69:443-53. Follow your healthcare provider's instructions about any restrictions on food, beverages, or activity. Flaxseed oil is a supplement that can boost your intake of omega-3 fatty acids. The phase IV clinical study analyzes what interactions people who take Flax seed and Aspirin have. Toulabi T, Yarahmadi M, Goudarzi F, Ebrahimzadeh F, Momenizadeh A, Yarahmadi S. Effects of flaxseed on blood pressure, body mass index, and total cholesterol in hypertensive patients: A randomized clinical trial. Flaxseed consumption may reduce blood pressure: A systematic review and meta-analysis of controlled trials. Flaxseed is a commonly recommended and used dietary supplement today. Pilot study to explore effects of low-fat, flaxseed-supplemented diet on proliferation of benign prostatic epithelium and prostate-specific antigen. Khalesi S, et al. 1995;49(3):169-178. View abstract. You can get the same amount of omega-3 fatty acids in your body by consuming fewer fish oil capsules. Summary: Drug interactions are reported among people who take Flaxseed and Metformin. Phytother Res 2021;35(7):3781-3791. Wang Wuyu suddenly woke up and sat up, his stomach made a loud noise like a drum beating. Other uses not proven with research have included enlarged prostate, heart disease, constipation, high blood pressure, irritable bowel syndrome, menopausal symptoms, weight loss, diverticulitis, attention deficit-hyperactivity disorder (ADHD), cancer (prostate, breast, lung, endometrial), and others. (n.d.). Alvarez-Perea A, Alzate -Prez D, Doleo Maldonado A, Baeza ML. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Which Supplements Should Be Avoided When Taking Statins Flaxseed (Linum usitatissimum) and flaxseed oil, which comes from flaxseed, are rich sources of the essential fatty acid alpha-linolenic acid a heart-healthy omega-3 fatty acid. Do not take this medication for more than 7 days unless directed by your doctor. While some studies support health claims, most are small, and more research is needed. Cotterchio M, Boucher BA, Manno M, et al. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Flaxseed interacts with 583 drugs . Phase II Trial of Flaxseed to Prevent Acute Complications After Chemoradiation for Lung Cancer. Do not give any herbal/health supplement to a child without medical advice. Cancer Causes Control 2008;19:259-72. Br J Nutr 2008;101:1145-9. However, you should always talk to your primary care provider to discuss flaxseed oil dosage and safety before adding the plant oil to your daily routine. Accessed Sept. 27, 2017. A total of 2 drugs are known to interact with Flax Seed Oil. 2020;29(1):61-67. Saarinen NM, Power K, Chen J, Thompson LU. Adolescent dietary phytoestrogen intake and breast cancer risk (Canada). Bacteria in the intestine convert some of the chemicals in flaxseed into lignans, which are thought to be responsible for many of the possible benefits of flaxseed. Flax has been used in alternative medicine as a possibly effective aid in treating type 2 diabetes, high cholesterol, and some autoimmune diseases such as systemic lupus erythematosus (SLE). Unlocking The Benefits Of Flaxseed: Does Ground Flaxseed Increase Edel AL, Rodriguez-Leyva D, Maddaford TG, Caligiuri SP, Austria JA, Weighell W, Guzman R, Aliani M, Pierce GN. Lancet 1982;2:1295-9. Dietary phytoestrogen intake--lignans and isoflavones--and breast cancer risk (Canada). Flaxseed oil. J Womens Health (Larchmt) 2008;17:355-66. Debra Rose Wilson, PhD, MSN, RN, IBCLC, AHN-BC, CHT. These types of drugs, herbs and supplements reduce blood clotting. View abstract. J Clin Endocrinol Metab 2005;90:1390-7. View abstract. Adlercreutz H, Heikkinen R, Woods M, et al. Ramon JM, Bou R, Romea S, et al. Chavarro JE, Stampfer MJ, Li H, et al. This is not a complete list of side effects and others may occur. Monitor your blood pressure closely. J Am Coll Nutr 1993;12:501-4. Barbiturate medicines that are prescribed for treating insomnia, controlling anxiety, or treating seizures may interfere with the effectiveness of the birth control pill. Rodriguez-Leyva D, Weighell W, Edel AL, LaVallee R, Dibrov E, Pinneker R, Maddaford TG, Ramjiawan B, Aliani M, Guzman R, Pierce GN. Variability in anticancer lignan levels in flaxseed. Prasad K, Mantha SV, Muir AD, Westcott ND. This content does not have an English version. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. (2008). Pan A, Sun J, Chen Y, et al. Herbal supplements and heart medicines may not mix Brouwer IA, Katan MB, Zock PL. Medically reviewed by Drugs.com on Jul 25, 2022. Curr Probl Cardiol 2022;47(7):100931. February 24, 2023. View abstract. Dietary intake of n-3 and n-6 fatty acids and the risk of prostate cancer. Dietary lignans and postmenopausal breast cancer risk by oestrogen receptor status: a prospective cohort study of Swedish women. Flaxseed oil is an oil made from pressed, ground flaxseeds. Medication Interactions That Can Cause the Pill to Fail - Verywell Health Omega 3 dietary sources include flax seeds, chia seeds, walnuts, and fish. However, research has shown that flax may not be effective in treating this condition. View abstract. View abstract. Possible drug interactions: Can reduce blood levels and effectiveness of many drugs, including birth control pills, cholesterol-lowering statins and some anti-HIV drugs. Eur J Clin Nutr 2007;61:1423-8. Verheus M, van Gils CH, Keinan-Boker L, et al. Coulman KD, Liu Z, Michaelides J, et al. Explore (NY) 2021. Low adherence may be a contributing factor leading to uncontrolled blood pressure in patients. Anaphylaxis caused by flaxseed. Do not take flax without medical advice if you are using any of the following medications: any medications for diabetes or high blood pressure; This list is not complete. Milder IE, Feskens EJ, Arts IC, et al. Potent antihypertensive action of dietary flaxseed in hypertensive patients. (2014). A double-blind, placebo-controlled and randomized study: flaxseed vs. safflower seed. Do not use this product without medical advice if you are breast-feeding a baby. This is one of the more common food-drug reactions. Things to remember when you fill your prescription. Flaxseed oil may be rich in omega-3 fatty acids, but it may not be the right type. Breast Cancer Res Treat 2000;64:49. Which Medications Should Not Be Taken With Turmeric? Drug Interactions Nutr Cancer 1992;17:153-9. View abstract. High alpha-linolenic acid flaxseed (Linum usitatissimum): some nutritional properties in humans. Therapeutic Research Faculty 2020. Teas have been used as a natural remedy to soothe stomach upset for thousands of years. Am J Clin Nutr 1999;69:549-55. Thompson LU, Rickard SE, Orcheson LJ, Seidl MM. View abstract. Are there supplements I should avoid when taking I apixaban (Eliquis Aitken-Saavedra J, Chaves Tarquinio SB, De Oliveira da Rosa WL, et al. There are 10 disease interactions with Cymbalta (duloxetine) which include: Liver Disease Renal Disease Depression Diabetes Glaucoma Hypertension Hyponatremia Mania Seizures Urinary Tract Obstruction Is it safe to eat raw flaxseed during pregnancy? You can learn more about how we ensure our content is accurate and current by reading our. Flaxseed oil also might decrease blood clotting. Dodin S, Lemay A, Jacques H, et al. J Diet Suppl 2011;8:257-65. Thanos J, Cotterchio M, Boucher BA, et al. Effects of dietary flaxseed lignan extract on symptoms of benign prostatic hyperplasia. One tablespoon of flaxseed oil has 7.26 grams. Flaxseed: a potential treatment for lupus nephritis. View abstract. Flax Seed vs. Drugs for High Blood Pressure View abstract. Mirghafourvand M, Mohammad-Alizadeh-Charandabi S, Ahmadpour P, Javadzadeh Y. View abstract. Most of the health benefits associated with omega-3 fatty acids from improving heart health to reducing inflammation are due to EPA and DHA, which come from fish and fish oil. Nutr Cancer 1999;33:188-95. Complement Ther Med. View abstract. Possible interactions include: Anticoagulant and anti-platelet drugs, herbs and supplements. 1. Yang C, Xia H, Wan M, et al. View abstract. Diclofenac (Voltaren, Cataflam, Voltaren-XR, Cambia) is a nonsteroidal anti-inflammatory medication prescribed to treat inflammation and pain caused by conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, bursitis, and menstrual cramps. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Systemic lupus erythematosus (SLE) nephritis, Constipation. Effects of dietary flaxseed in women with cyclical mastalgia. Urology 2001;58:47-52. You may find that flaxseed oil leads to diarrhea. Plasma enterolignans are associated with lower colorectal adenoma risk. Keep in mind the FDA does not recommend Trulicity as a "first-line therapy" for . If you have a condition or take a medication that lowers your blood pressure, adding this supplement to your diet could cause complications. View abstract. Cancer Epidemiol Biomarkers Prev 2007;16:1364-70. View abstract. For many, the benefits of flax seeds and flaxseed oil may outweigh the risks of using the product. Determination of urinary lignans and phytoestrogen metabolites, potential antiestrogens and anticarcinogens, in urine of women on various habitual diets. Accessed Sept. 27, 2017. Eating a flaxseed muffin daily for 3 months or taking flaxseed powder by mouth daily for 2 months seems to reduce breast pain that occurs at the start of the, Obesity. The grapefruit causes larger amounts of the medication to stay in your body for a longer period of time, explains Mayo Clinic nutritionist Katherine Zeratsky 3. Demark-Wahnefried W, Polascik TJ, George SL, et al. The Problem With Flaxseed And Thyroid Function. However, it may cause undesirable side effects if you have a preexisting medical condition, use certain medications, or take the wrong dosage. Thompson LU, Chen JM, Li T, et al. Eur J Nutr 2022;61(3):1377-1389. Pan A, Demark-Wahnefried W, Ye X, et al. Exp Biol Med (Maywood) 2007;232:1071-80. Can Flaxseed Help Thyroid Problems - Thyroid Advisor View abstract. There is a chance you may have an allergy to flax seeds and flaxseed oil. Milk Thistle: Drug Interactions & Contraindications | Study.com 4. Dietary flaxseed independently lowers circulating cholesterol and lowers it beyond the effects of cholesterol-lowering medications alone in patients with peripheral artery disease. To be as proactive as possible, consult your doctor about using flaxseed oil as a dietary supplement before you begin to use it. Black Seed Oil and Diabetes: What's Known, What's Not, Harvard T.H. Cockerell KM, Watkins AS, Reeves LB, et al. Alpha-linolenic acid in the treatment of rheumatoid arthritis. The Top Cat Supplements For Optimal Feline Health - Camelus J Res Med Sci. It may take 1 to 3 days before this medication starts working. the unsubscribe link in the e-mail. Your body is an amazing physiological machine. Menopause 2012;19:48-53. Flaxseed - Phenacemide Interaction Details | HelloPharmacist Flaxseed reduces total and LDL cholesterol concentrations in Native American postmenopausal women. are using nonsteroidal anti-inflammatory drugs. Oncology Nutrition advises that you should discuss the use of flax seeds with your doctor and avoid the use of flaxseed oil altogether because it provides no benefit to those with prostate cancer. This will help prevent any negative reactions that might arise. Flax Uses, Side Effects & Warnings - Drugs.com Leon F, Rodriguez M, Cuevas M. Anaphylaxis to Linum. National Center for Complementary and Integrative Health. Ingredients: Stichopus Horrens Extract: Gamodulin Chlorella Vitamin E (dl-alpha-tocopherol) Flaxseed oil Direction Of Use: Adult 15ml each time, twice a day Twice a day preferably to be taken on empty stomach. 2020;152:104622. View abstract. View abstract. Accessed Sept. 27, 2017. View abstract. This article reviews the benefits, safety, and side, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Cursed Get lost, blood pressure medication lawsuit change back to my little brat s appearance, or I won t be able to support you. Nutr J 2011;10:44. These medications may interact and cause very harmful effects. Flaxseed reduces some risk factors of cardiovascular disease. Medicinal use of this product has not been approved by the FDA. Accessed Sept. 27, 2017. Please contact your doctor or pharmacist. Diarrhea Or Constipation Advertisements One likely effect is on the digestive system. Am J Clin Nutr 2004;80:204-16. However, because antibiotics kill these bacteria, lignans might not be formed as usual. Similar to any other medication, Trulicity (dulaglutide) may interact with certain drugs or health conditions. View abstract. View abstract. Plant- and marine-derived n-3 polyunsaturated fatty acids have differential effects on fasting and postprandial blood lipid concentrations and on the susceptibility of LDL to oxidative modification in moderately hyperlipidemic subjects. 2021;60(1):287-298. Valley Medical Center | Flaxseed Can Flaxseed Help Thyroid Problems? - ThyroMate J Nutr 2010;140:1937-42. When taken in recommended amounts, flaxseed and flaxseed oil are generally safe to use. Mayo Clinic does not endorse any of the third party products and services advertised. Read about how you can use flaxseed oil . Chen J, Power KA, Mann J, et al. See a medical center immediately if your reaction to flaxseed oil causes your throat to tighten or shortness of breath. Dangers of taking flaxseed oil while taking thyroid medication - HealthTap J Allergy Clin Immunol 1996;98:469-70. Information from this source is evidence-based and objective, and without commercial influence. Rose DP. Flaxseed is high in soluble fiber and in lignans, which contain phytoestrogens. Role of Plant-Derived Omega-3 Fatty Acids in Human Nutrition. Pharmacol Res. View abstract. Rheumatol Int 1995;14:231-4. Am J Clin Nutr 2006;84:400-5. Taking flaxseed along with diabetes medications might cause blood sugar to drop too low. Salmon, wild - bone loss, joint pain. Flaxseed oil is generally cold pressed. Follow all directions on the product label and package. Not all possible interactions are listed in this product guide. Am J Clin Nutr 1999;69:395-402. [3] . J Nutr. View abstract. Cancer Lett 1991;60:135-42. Though your body contains enzymes that convert ALA from flaxseed oil into EPA and DHA, your body only converts 10 to 15 percent of the ALA, says Harvard Health Publishing. Hadi A, Askarpour M, Salamat S, Ghaedi E, Symonds ME, Miraghajani M. Effect of flaxseed supplementation on lipid profile: An updated systematic review and dose-response meta-analysis of sixty-two randomized controlled trials. Maternal flaxseed diet during pregnancy or lactation increases female rat offspring's susceptibility to carcinogen-induced mammary tumorigenesis. information is beneficial, we may combine your email and website usage information with Khalatbari Soltani S, Jamaluddin R, Tabibi H, Mohd Yusof BN, Atabak S, Loh SP, Rahmani L. Effects of flaxseed consumption on systemic inflammation and serum lipid profile in hemodialysis patients with lipid abnormalities. Flax seed oil is used to treat the following conditions: Atopic Dermatitis; Constipation; Eczema; High Cholesterol; Peripheral Neuropathy; Prostate Cancer; green tea. Caligiuri SP, Aukema HM, Ravandi A, Guzman R, Dibrov E, Pierce GN. View abstract. 2013 Apr;16(4):357-60. Moderate to vigorous physical activity, particularly aerobic exercise, has been shown to be associated with lower risk of bone fractures in women being treated with aromatase inhibitors. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Flaxseed - Technetium Tc-99m Exametazime Interaction Hypertension. Copyright 1996-2023 Cerner Multum, Inc. What medications does flaxseed interfere with? Advertising revenue supports our not-for-profit mission. Lemay A, Dodin S, Kadri N, et al. A high dose of flaxseed reduces the production of pro-inflammatory eicosanoids such as thrombozane A2 and other lipids mediators like platetet-activating factor (PAF). (2016). Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, There are many studies currently under way, flax seeds may increase your chances of bleeding, Interactions with medications and health conditions, nccih.nih.gov/health/flaxseed/ataglance.htm, mayoclinic.org/drugs-supplements/flaxseed-and-flaxseed-oil/background/hrb-20059416, oncologynutrition.org/erfc/healthy-nutrition-now/flaxseed-prostate-cancer-risk/, pennstatehershey.adam.com/content.aspx?productId=107&pid=33&gid=000959, mayoclinic.org/what-are-omega-3-fatty-acids-from-fish-oil/art-20232583, health.harvard.edu/heart-health/why-not-flaxseed-oil, 6 Benefits of Flaxseed Oil Plus How to Use It. JAMA 2005;294:1493-1504. No, it's not always safe to take flaxseed oil with other medications. Review/update the Clin Nutr. Barre DE, et al. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Effect of flaxseed consumption on flow-mediated dilation and inflammatory biomarkers in patients with coronary artery disease: a randomized controlled trial. View abstract. A randomized controlled trial of the effect of dietary soy and flaxseed muffins on quality of life and hot flashes during menopause. Call your doctor if the condition you are treating with flax does not improve, or if it gets worse while using this product. Who should not consume flaxseed? - sdnimik.bluejeanblues.net Flaxseed and cardiovascular risk. Epiandrosterone . Does Flaxseed Interfere With Blood Pressure Medication: Can You Eat Javidi A, Mozaffari-Khosravi H, Nadjarzadeh A, Dehghani A, Eftekhari MH. 1 Severe Side Effects Dietary phytoestrogens and lung cancer risk. Effect of flaxseed consumption on urinary estrogen metabolites in postmenopausal women. Anticancer Res 1998;18:1405-8. Other drugs may interact with flax, including prescription and over-the-counter medicines, vitamins, and herbal products. View abstract. View abstract. Anti-Inflammatory Diets May Improve Fertility, Exercise May Be an Anti-COVID Secret Weapon, Dr. Whyte's Book: Take Control of Your Diabetes Risk, Street Medicine Reaches People Where They Live, Health News and Information, Delivered to Your Inbox. According to WebMD, "Research suggests that plant omega-3s help the cardiovascular system through several different mechanisms, including anti-inflammatory action and normalizing the heartbeat. Mousavi Y, Adlercreutz H. Enterolactone and estradiol inhibit each other's proliferative effect on MCF-7 breast cancer cells in culture. Available for Android and iOS devices. This means multiple trips to the bathroom to alleviate bloating, stomach pain, constipation, diarrhea, and the like. List Flaxseed side effects by likelihood and severity. Some medications that may interact with flaxseed oil negatively include: You should consult your doctor before using flaxseed oil if you have: Pregnant and nursing women should avoid the use of flaxseed oil. View abstract. View abstract. View abstract. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Flaxseed and Metformin drug interactions - eHealthMe Negative Effects of Flaxseed Meal | livestrong Does Fish Oil Interfere With Metformin | DiabetesTalk.Net Healthline Media does not provide medical advice, diagnosis, or treatment. View abstract. Flaxseed improves lipid profile without altering biomarkers of bone metabolism in postmenopausal women. View abstract. Consult your doctor before relying on flaxseed oil to boost your omega-3 fatty acid levels to ensure youre using the supplement safely. Learn about the medical uses, claims, and side effects of flaxseed. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. The authors of the article in the Journal of Food Science and Technology call flaxseed oil a functional food because of its potential health benefits. health information, we will treat all of that information as protected health Flaxseed oil may be a good option for you. Fink BN, Steck SE, Wolff MS, et al. Hrt-interactions | The Surmeno Connection Flaxseed is used for constipation, diabetes, high cholesterol, obesity, and swelling of the kidneys in people with lupus. Effects of flaxseed supplementation on functional constipation and quality of life in a Chinese population: A randomized trial. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Flaxseed and its lignan and oil components reduce mammary tumor growth at a late stage of carcinogenesis. Azrad M, Vollmer RT, Madden J, Dewhirst M, Polascik TJ, Snyder DC, Ruffin MT, Moul JW, Brenner DE, Demark-Wahnefried W. Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer. (2013). Flaxseed oil may also lower insulin and improve antioxidant activity in people with Type 2 diabetes, according to a July 2019 randomized, double-blind, placebo-controlled study published in Phytotherapy Research. Khalesi S, Irwin C, Schubert M. Flaxseed consumption may reduce blood pressure: a systematic review and meta-analysis of controlled trials. other information we have about you. How fast does psyllium work? View abstract. Flaxseed dietary supplement versus hormone replacement therapy in hypercholesterolemic menopausal women. View abstract. Oral drugs.