steve kirsch fluvoxamine

This give another 50% of benefit. Paper reviewing the evidence and mechanisms of action for fluvoxamine: Lenze Phase 2 RCT published Nov 12, 2020: Seftel RWE trial that confirmed the Phase 2 trial published Feb 1, 2021. Those days are gone. 19 In addition, several . This suggests that a 50mg BID loading dose for day one, followed by 50mg QD dose for the following 13 days should also be quite effective. When was the last time you saw a phase 3 fail where there was a 100% effect size in both an RCT and RWE study along with 4 independent observational trials all showing a positive effect, and there is clear mechanism of action where there is less than a 1% chance that it is not working (the SSRI's ordered their impact based on their Sigma activation which is 1 in 120 options), and where in every single case we are aware of the patient taking the drug reversed to normal in an average of 3 days? The NIH Guidelines committee is being very slow to react (we have no idea if they are even considering the drug because nobody is allowed to know that because all their deliberations are kept secret). How covid-19 conspiracy videos keep getting millions of views. Kirsch and his group received a fresh wave of attention off hopeful trials of the antidepressant fluvoxamine, which ultimately won him a spot on 60 Minutes in March. Fluvoxamine, created 37 years ago, is an inexpensive and widely available generic drug. Compulsive fiddling with your mask? This was shown to be very tolerable (no side effects in 99% of patients) and extremely effective (no hospitalizations and death if you start it ASAP after first symptoms). The ICER independent review showed fluvoxamine is more effective than Molnupiravir: Read this article I wrote about using fluvoxamine correctly for COVID. But fear of trying something new prevents any doctor from giving this drug a try. Elsewhere he has said he began questioning vaccine safety after an unnamed Twitter follower told him several family members died after getting their shots. After two weeks (since it was a tight knit community, everyone could see what was happening to the two groups), every track worker who got sick with COVID, demanded the drug. Doctors who have used fluvoxamine in the US and other countries swear by it. It is very safe: There is no evidence fluvoxamine is harmful and led to a worse outcome. Here's why. How I recommend people treat COVID and the fascinating backstory of how fluvoxamine was discovered. Mouse Systems is not a household word, he told the journalist. Please read and agree to the disclaimer before watching this video.. Steve Kirsch On COVID Early Treatment and CensorshipSteve Kirsch is an entrepreneur and . Earlier that month, Seftel had heard about fluvoxamine during a presentation by tech entrepreneur Steve Kirsch, whose COVID-19 Early Treatment Fund supports research on existing drugs that could . Here is the latest version. I think so. @stkirsch. It was not compatible with his position as CEO to continue taking a very public stance on the vaccines, Richard Char, M10s general counsel, told me. 1 hr ago. Late in the session, minutes before this impromptu video wrap up, Tip o' Spear Steve Kirsch addressed the panel and revealed that the FDA had just shot down Fluvoxamine as an approved COVID treatment. My favorite dosage is 50mg twice a day for 14 days. Thanks for working tirelessly to help others. Think about it Molnupiravir has a 50% risk reduction whereas fluvxoamine is over 90%. Everyone says "we need more data" to show fluvoxamine works for COVID. None of this would really matter if Kirschs views on vaccinations were private, or shared with a limited audience. But while this effort was praiseworthy, Kirsch's predilection for oversimplifying and exaggerating led him to mislead. On his blog, Covid-19 Data Science, he has extensivelyand mercilesslyunpacked Kirschs evidence for the vaccine death claims. Medicine today isnt about saving your life. Doctors wait for government permission (EUA or added to the NIH guidelines) before using a drug. are all super cheap, effective, and available without a prescription. Nobody who took the drug got sick at all, most all wanted to return to work within 3 days after starting treatment. The group who declined the drug were very sick with 12.5% requiring hospitalization and one died. Jeffrey Glenn, an infectious disease professor at Stanford University, calls the inaction on the current evidence on the table "criminal.". I didnt intend to spend a lot of time on Steve in particular, but that video was so influential.. Doctors who have used fluvoxamine in the US and other countries swear by it. In severe cases, it takes longer. Weve known it works since August 24, 2020. . and here are the slides I used in, Collections of op-eds and presentations about fluvoxamine, Please see my answer on Quora Its whether Merck can make a killing that matters. But they dont want their names used. Steve Kirsch is an inventor of the optimal mouse, a Silicon Valley millionaire, and an MIT alum (Class of '80). This story is part of the Pandemic Technology Project, supported by The Rockefeller Foundation. Sage Hana. All have had a 100% success record in keeping their patients out of the hospital. My experience is very typical. Its all about NIH saying it is OK. Medicine today is driven by government opinion, not science. 95% confidence effect size is 75% or more. So why would we wait when lives are being lost? To protect M10 from my COVID-19 vaccination opinions, I will no longer post about my vaccination concerns here.. Im not going to make the same mistake again.. They knew in advance it was coming and on the day the paper was published they ignored it entirely. At the end of May this year, Siliciano emailed the other advisors to say that Kirsch had gone off the deep end and he was cutting ties. Fluvoxamine, Proxalutamide, and Ivermectin: 100% success I'm very bullish on two drug combos since it is rare for Read More The best COVID treatments for hospitalized patients Seven treatments for hospitalized COVID patients with very high success rates. You can experience serious side effects if you do not pay attention to interactions such as if you are currently on another SSRI of a different type. Perhaps Kirschs most effective tactic, though, is simply his willingness to outlast everyone else. Worst case, if we ignore all additional evidence so the average is a 60% pass rate. All this was known back in January 2021 when a key opinion leader panel of experts from NIH, CDC, FDA, academia, and journal editors voted by over 2:1 to recommend that fluvoxamine be recommended to physicians to discuss with patients. I couldnt tell I was on the drug. Their willingness to lie did. He's discovered a common medication that's highly effective in minimizing the impacts of COVID-19 - two studies have proven so. Proxalutamide and fluvoxamine pushers and the early treatment grift. YouTube , , , fluvoxamine, , , , , , , , , , . There were IRB rules that required the 65 patients to be listed in the diagrams and charts. This should be top news, but the press is ignoring this and attempt to write stories about it are killed by the editors. Steve Kirsch is a high-tech serial entrepreneur based in Silicon Valley. Then he hosted a superspreader event. Some are views most scientists think are wrong. In October, the group reported that, while a few patients in the placebo group ended up in the hospital, none of the patients receiving fluvoxamine got sick enough to go. If you cant lay off the java, then try fluoxetine (Prozac). In that same IEEE Spectrum story about his then-new startup, Propel Software, he said he felt successful, but not famous. Steve Kirsch is baffled. Once the Phase 2 result came out, it should have been embraced by doctors. It is about following orders and making money for the drug companies and protecting the doctor from liability and losing his medical license. Hes also made several videos and podcasts with Vladimir Zelenko, the conspiracy theorist doctor who convinced Trump to take hydroxychloroquine. The ongoing battle between social-media companies and covid-19 misinformation pushersincluding US president Donald Trumpstepped up again this week thanks to a new viral video. That way you can start immediately. Fluvoxamine is a well-tolerated, widely available, inexpensive selective serotonin reuptake inhibitor that has been shown in a small, double-blind, placebo-controlled, randomized study to prevent clinical deterioration of patients with mild coronavirus disease 2019 (COVID-19). Dr. Seftel is an NIH-funded researcher and an NIH reviewer. Flavio Cadegiani and Steve Kirsch's studies didn't make the cut. Nobody in the medical community is speaking out about how hypocritical the medical community is for ignoring the positive Phase 3 trial results and instead following whatever the NIH or FDA says. This 1/6 of the dose the FDA has approved for OCD (the labelled indication for fluvoxamine)! 36m "We found Fauci was the most highly compensated federal employee. All can merit a fluvoxamine prescription based on traditional diagnoses. Nov 12: Steve Kirsch gives talk on CETF to HarvardBusiness School hosted by Dr. Seftel Nov 13:Mass COVID outbreak at GGF is now publiclyknown Nov 16: Seftel, the track physician at GGF, startsFLV . Since FLV is a safe drug, it should have been widely discussed with patients that there is virtually no downside and a huge reduction in hospitalization if the drug is given early. Why not fluvoxamine? Jan 17. CETF founder Steve Kirsch accepted an invitation to discuss the findings on a weekly . Jeffrey Morris, director of biostatistics at the University of Pennsylvania Perelman School of Medicine, has made debunking Kirschs claims something of a hobby. In it, he claimed mRNA vaccines kill one in 5,000 recipients and dramatically increase the rate of miscarriages. Ivermectin has a very high quality systematic review, the highest possible level in Evidence Based Medicine. Even though they spent only 45 minutes and just reviewed the 2 clinical studies and some plausible mechanisms of action (and ignored anecdotal evidence and multiple retrospective trials, all of which were supportive), after the meeting they voted overwhelmingly (11 to 5 with 4 being neutral) in favor of having doctors talk to their patients about using fluvoxamine if they have COVID using a "shared decision making" process. It is very important to educate doctors because most people rely on their doctors for advice. This looks ominous, but it harmless. It was 25 years ago yesterday that Andrew Wakefield launched the modern iteration of the antivaccine movement.In doing so, he laid down a template that antivax quacks today still follow. P-value was 10^-14 on that study (done by Dr. This site requires JavaScript to run correctly. If there is a better drug on the table today than fluvoxamine, the NIH panel should put that one on the guidelines. Substitutions. It has shown to be 100% protective of hospitalization in 2 clinical trials. Those days are gone. Keeping this drug off the NIH Guidelines does nothing to reduce the death rate. On January 22, 2021, thirty key opinion leaders (KOL) from NIH, CDC, and leading academic institutions met to review the evidence for using fluvoxamine for treating COVID. of the 'intellectual dark web '" and allowed him to access a "large and receptive audience to his claims about a fluvoxamine conspiracy". Food/drugs to avoid while on fluvoxamine. The FDA approved Molnupiravir which was less effective. 90,000 people don't have to die in the next 3 weeks. Medicine has been transformed to doing whatever the NIH/FDA says, regardless of how many lives will be lost. Most recent articles first. We don't know why the NIH panel is ignoring fluvoxamine and we aren't allowed to find out. Pretty much nothing changed when the Phase 3 trial confirmed fluvoxamine worked. The study was also featured on 60 Minutes. I agreed to do it partially because I respect Bob [Siliciano] so much, and partially because I thought the concept was excellent, said former board member Doug Richman, a prominent HIV drug researcher at the University of California San Diego and former member of the funds scientific advisory board. He has made millions from these projects, even if they have not turned him into a household name. Comparison with molnupiravir. Former Silicon Valley tech executive Steve Kirsch, a philanthropist and Substack author who created the COVID-19 Early Treatment Fund (CETF) to fund researchers working on repurposed drugs, including fluvoxamine, which reduces death from COVID by a factor of 12. And, according to three members of CETF's scientific advisory board, he put pressure on them to promote fluvoxamine for clinical use without conclusive data that it worked for . In some cases, youd want to taper down the dosage. . The race to find covid-19 drug treatments that actually work, The antimalarial drug Trump took for covid might actually be dangerous. Fluvoxamine is a very safe drug on market for 37 years, tens of millions of people have taken it, no record in scientific literature of anyone dying on overdose, and according to doctors that know the drug the best, about as dangerous as taking a Tylenol. The differences are obvious to untrained eyes. But Kirsch is also motivated by an unsatisfied competitive streak. The post read: "I will be featured on 60 Minutes this Sunday talking about fluvoxamine as an effective treatment for COVID-19 to prevent hospitalization and death. Its actually much harder to parse out a signal than if youre treating diabetes or cancer., In addition to the issues with fluvoxamine, advisors grew increasingly uncomfortable with Kirschs posts about ivermectin, which he has repeatedly claimed in blog posts and appearances in alternative media can be used together with fluvoxamine to prevent 100% of covid-19 deaths. (article I did after the TOGETHER trial). Try refreshing this page and updating them one All the medical journals refused to publish the meeting notes (rejected by 6 journals). The man who ran Risperdal sales, Alex Gorsky, is now CEO of Johnson & Johnson. He pushes fluvoxamine, an anti-depression drug which despite doing very well in covid treatment studies has been strangely neglected. The NIH wrote a bullshit rejection because the FDA told them not to approve it. He wrote on his personal website that hed been advised that being associated with the drug would immediately trash my credibility.. It is currently approved for treatment of depression and obsessive compulsive disorder (OCD). Los Altos Hills resident Steve Kirsch funded research into the drug fluvoxamine as a treatment for COVID-19. Ive talked to doctors who are extremely familiar with the drug and all the trial results and they would prescribe it to their patients. This is quite stunning because the PK of the drug done at the Gates Foundation shows it only reaches 50% of the final concentration after 3 days. No long haul symptoms if you start the drug ASAP after first symptoms. Where did it go wrong. ICER: But an Editor's Note urged physicians to treat this as a hypothesis and not as a basis for clinical decision-making. The data we have today with just 2 clinical trials (RCT and confirmatory RWE) is compelling. The paramedics will think you are on drugs. Both of them encouraged anyone reading this article to get vaccinated. From the French observational data (see the very last page), it appears that the biggest effect is limiting serotonin release (any SSRI will do that). This is a more comprehensive look at the key evidence supporting fluvoxamine: Hear from the doctors who did the studies directly as well as the Dean of Medicine at Emory University: List of the best evidence-based COVID treatment options. After publication of the recommendation in December 2021, the NIH did absolutely nothing change their recommendation. We report a real-world experience using fluvoxamine for coronavirus disease 19 (COVID-19) in a prospective cohort in the setting of a mass outbreak. just like ivermectin). . Several former members told me he began relentlessly pressuring them to promote the drug in media stories, often during exhausting, circuitous conversations. . Please. Repurposed drugs are safer and more effective than the current vaccines. I only know of a few doctors who prescribe this off-label, all with 100% success rates. Fluvoxamine is the poster child of the COVID-19 Early Treatment Fund (CETF). Steve Kirsch. Why the FDA should grant an EUA for fluvoxamine immediately, Links to evidence about fluvoxamine including the public data repository, Here's the first one: P-value was 10^-14 on that study (done by Dr. Seftel). Three of the four outpatient trials have been reported out: all were successful. We could have saved a lot of lives. If you do have a side-effect, it is usually mild nausea which goes away when you stop taking the drug. Server IP cope with resolved: Yes Http reaction code: 200 Response time: 0.27 sec. This drug can save your life but you have to ask for it! Fluvoxamine is a selective serotonin reuptake inhibitor (SSRI), a class of anti-depressants, mostly prescribed for people suffering from an obsessive-compulsive disorder. Steve Kirsch is a high-tech serial entrepreneur based in Silicon Valley. It used to be that a Phase 3 study would do it. Our in-depth reporting reveals whats going on now to prepare you for whats coming next.

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